Contribution of mobile genetic elements toDesulfovibrio vulgarisgenome plasticity

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Contribution of mobile genetic elements to Desulfovibrio vulgaris genome plasticity.

The genome of Desulfovibrio vulgaris strain DePue, a sulfate-reducing Deltaproteobacterium isolated from heavy metal-impacted lake sediment, was completely sequenced and compared with the type strain D. vulgaris Hildenborough. The two genomes share a high degree of relatedness and synteny, but harbour distinct prophage and signatures of past phage encounters. In addition to a highly variable ph...

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Bacterial genomes vary widely in gene content [1]. This variation can be the result of different evolutionary events including gene loss, gene duplication, and horizontal gene transfer [2]. Mobile genetic elements such as plasmids and viruses are major vehicles to transfer genes between different cells, and thus play a key role in the evolution and diversification of bacteria [3]. To understand...

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Because transposons are able to self-excise and self-insert into the genome, they can also be used as a tool for altering gene expression, especially in the case of transposon mutagenesis. Here, Meredith et al. describe a robust transposon mutagenesis system that they have created allowing for the creation of a large range of expression genotypes in S. aureus. This collection has allowed for th...

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ژورنال

عنوان ژورنال: Environmental Microbiology

سال: 2009

ISSN: 1462-2912,1462-2920

DOI: 10.1111/j.1462-2920.2009.01946.x